Polymorphic Allele of Human IRGM1 Is Associated with Susceptibility to Tuberculosis in African Americans

An ancestral polymorphic allele of the human autophagy-related gene IRGM1 is associated with altered gene expression and a genetic risk for Crohn's Disease (CD). We used the single nucleotide polymorphism rs10065172C/T as a marker of this polymorphic allele and genotyped 370 African American an...

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Detalles Bibliográficos
Autores principales: King, Katherine Y., Lew, Justin D., Ha, Ngan P., Lin, Jeffery S., Ma, Xin, Graviss, Edward A., Goodell, Margaret A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025014/
https://www.ncbi.nlm.nih.gov/pubmed/21283700
http://dx.doi.org/10.1371/journal.pone.0016317

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