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Diet-Induced Obesity Impairs Endothelium-Derived Hyperpolarization via Altered Potassium Channel Signaling Mechanisms

BACKGROUND: The vascular endothelium plays a critical role in the control of blood flow. Altered endothelium-mediated vasodilator and vasoconstrictor mechanisms underlie key aspects of cardiovascular disease, including those in obesity. Whilst the mechanism of nitric oxide (NO)-mediated vasodilation...

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Detalles Bibliográficos
Autores principales:	Haddock, Rebecca E., Grayson, T. Hilton, Morris, Margaret J., Howitt, Lauren, Chadha, Preet S., Sandow, Shaun L.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025034/ https://www.ncbi.nlm.nih.gov/pubmed/21283658 http://dx.doi.org/10.1371/journal.pone.0016423

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