DNA binding - dependent glucocorticoid receptor activity promotes adipogenesis via krüppel-like factor 15 gene expression

Glucocorticoids, such as dexamethasone (Dex), have been used as in vitro inducers of adipogenesis. However, the roles of the glucocorticoid receptor (GR) in adipogenesis have not been well characterized yet. Here we show that inhibition of GR activity using the GR antagonist RU486 prevents human mes...

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Detalles Bibliográficos
Autores principales: Asada, Maki, Rauch, Alexander, Shimizu, Hirohito, Maruyama, Hiromi, Miyaki, Shigeru, Shibamori, Masafumi, Kawasome, Hideki, Ishiyama, Hironobu, Tuckermann, Jan, Asahara, Hiroshi
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025047/
https://www.ncbi.nlm.nih.gov/pubmed/20956975
http://dx.doi.org/10.1038/labinvest.2010.170

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