Mechanism of the Ca(2+)-Dependent Interaction between S100A4 and Tail Fragments of Nonmuscle Myosin Heavy Chain IIA

The interaction between the calcium-binding protein S100A4 and the C-terminal fragments of nonmuscle myosin heavy chain IIA has been studied by equilibrium and kinetic methods. Using site-directed mutants, we conclude that Ca(2+) binds to the EF2 domain of S100A4 with micromolar affinity and that th...

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Detalles Bibliográficos
Autores principales: Badyal, Sandip K., Basran, Jaswir, Bhanji, Nina, Kim, Ju Hwan, Chavda, Alap P., Jung, Hyun Suk, Craig, Roger, Elliott, Paul R., Irvine, Andrew F., Barsukov, Igor L., Kriajevska, Marina, Bagshaw, Clive R.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025356/
https://www.ncbi.nlm.nih.gov/pubmed/21110983
http://dx.doi.org/10.1016/j.jmb.2010.11.036

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