Cargando…

Epigenetic engineering shows H3K4me2 is required for HJURP targeting and CENP-A assembly on a synthetic human kinetochore

Kinetochores assemble on distinct ‘centrochromatin' containing the histone H3 variant CENP-A and interspersed nucleosomes dimethylated on H3K4 (H3K4me2). Little is known about how the chromatin environment at active centromeres governs centromeric structure and function. Here, we report that ce...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bergmann, Jan H, Rodríguez, Mariluz Gómez, Martins, Nuno M C, Kimura, Hiroshi, Kelly, David A, Masumoto, Hiroshi, Larionov, Vladimir, Jansen, Lars E T, Earnshaw, William C
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025471/ https://www.ncbi.nlm.nih.gov/pubmed/21157429 http://dx.doi.org/10.1038/emboj.2010.329

Ejemplares similares

CENP-C and CENP-I are key connecting factors for kinetochore and CENP-A assembly
por: Shono, Nobuaki, et al.
Publicado: (2015)

Epigenetic engineering shows that a human centromere resists silencing mediated by H3K27me3/K9me3
por: Martins, Nuno M. C., et al.
Publicado: (2016)

CENP-B creates alternative epigenetic chromatin states permissive for CENP-A or heterochromatin assembly
por: Otake, Koichiro, et al.
Publicado: (2020)

HJURP is a CENP-A chromatin assembly factor sufficient to form a functional de novo kinetochore
por: Barnhart, Meghan C., et al.
Publicado: (2011)

Breaking the HAC Barrier: Histone H3K9 acetyl/methyl balance regulates CENP-A assembly
por: Ohzeki, Jun-ichirou, et al.
Publicado: (2012)

Xenopus HJURP and condensin II are required for CENP-A assembly
por: Bernad, Rafael, et al.
Publicado: (2011)

Xenopus HJURP and condensin II are required for CENP-A assembly
por: Bernad, Rafael, et al.
Publicado: (2011)

KAT7/HBO1/MYST2 Regulates CENP-A Chromatin Assembly by Antagonizing Suv39h1-Mediated Centromere Inactivation
por: Ohzeki, Jun-ichirou, et al.
Publicado: (2016)

Nap1 regulates proper CENP-B binding to nucleosomes
por: Tachiwana, Hiroaki, et al.
Publicado: (2013)

Combination of CENP-B Box Positive and Negative Synthetic Alpha Satellite Repeats Improves De Novo Human Artificial Chromosome Formation
por: Okazaki, Koei, et al.
Publicado: (2022)

Epigenetic engineering reveals a balance between histone modifications and transcription in kinetochore maintenance
por: Molina, Oscar, et al.
Publicado: (2016)

H3K9me3 maintenance on a human artificial chromosome is required for segregation but not centromere epigenetic memory
por: Martins, Nuno M. C., et al.
Publicado: (2020)

Histone H4 Lys 20 Monomethylation of the CENP-A Nucleosome Is Essential for Kinetochore Assembly
por: Hori, Tetsuya, et al.
Publicado: (2014)

HJURP interaction with the condensin II complex during G1 promotes CENP-A deposition
por: Barnhart-Dailey, Meghan C., et al.
Publicado: (2017)

Mechanism of centromere recruitment of the CENP-A chaperone HJURP and its implications for centromere licensing
por: Pan, Dongqing, et al.
Publicado: (2019)

Repression of CENP-A assembly in metaphase requires HJURP phosphorylation and inhibition by M18BP1
por: Flores Servin, Julio C., et al.
Publicado: (2023)

Generation of a Synthetic Human Chromosome with Two Centromeric Domains for Advanced Epigenetic Engineering Studies
por: Pesenti, Elisa, et al.
Publicado: (2018)

Inactivation of a Human Kinetochore by Specific Targeting of Chromatin Modifiers
por: Nakano, Megumi, et al.
Publicado: (2008)

HJURP antagonizes CENP-A mislocalization driven by the H3.3 chaperones HIRA and DAXX
por: Nye, Jonathan, et al.
Publicado: (2018)

Unraveling the Role of Histone Variant CENP-A and Chaperone HJURP Expression in Thymic Epithelial Neoplasms
por: Levidou, Georgia, et al.
Publicado: (2022)

Stable complex formation of CENP-B with the CENP-A nucleosome
por: Fujita, Risa, et al.
Publicado: (2015)

Correction: HJURP antagonizes CENP-A mislocalization driven by the H3.3 chaperones HIRA and DAXX
Publicado: (2018)

CENP-A nucleosome clusters form rosette-like structures around HJURP during G1
por: Andronov, Leonid, et al.
Publicado: (2019)

Characterization of the Kinetochore Binding Domain of CENP-E Reveals Interactions with the Kinetochore Proteins CENP-F and hBUBR1
por: Chan, G.K.T., et al.
Publicado: (1998)

Molecular basis for CENP-N recognition of CENP-A nucleosome on the human kinetochore
por: Tian, Tian, et al.
Publicado: (2018)

Molecular basis of outer kinetochore assembly on CENP-T
por: Huis in 't Veld, Pim J, et al.
Publicado: (2016)

Calcium depletion destabilises kinetochore fibres by the removal of CENP-F from the kinetochore
por: Phengchat, Rinyaporn, et al.
Publicado: (2017)

Distinct organization and regulation of the outer kinetochore KMN network downstream of CENP-C and CENP-T
por: Rago, Florencia, et al.
Publicado: (2015)

Method to Assemble Genomic DNA Fragments or Genes on Human Artificial Chromosome with Regulated Kinetochore Using a Multi-Integrase System
por: Lee, Nicholas C. O., et al.
Publicado: (2017)

Auxin/AID versus conventional knockouts: distinguishing the roles of CENP-T/W in mitotic kinetochore assembly and stability
por: Wood, Laura, et al.
Publicado: (2016)

CENP-E Function at Kinetochores Is Essential for Chromosome Alignment
por: Schaar, B.T., et al.
Publicado: (1997)

Kinetochore–microtubule attachment throughout mitosis potentiated by the elongated stalk of the kinetochore kinesin CENP-E
por: Vitre, Benjamin, et al.
Publicado: (2014)

CDK1-mediated CENP-C phosphorylation modulates CENP-A binding and mitotic kinetochore localization
por: Watanabe, Reito, et al.
Publicado: (2019)

The CENP-S complex is essential for the stable assembly of outer kinetochore structure
por: Amano, Miho, et al.
Publicado: (2009)

The pseudo GTPase CENP-M drives human kinetochore assembly
por: Basilico, Federica, et al.
Publicado: (2014)

Lessons learned from counting molecules: how to lure CENP-A into the kinetochore
por: Scott, Kristin C., et al.
Publicado: (2014)

HJURP puts the centromere in place
por: Short, Ben
Publicado: (2011)

SUMOylated NKAP is essential for chromosome alignment by anchoring CENP-E to kinetochores
por: Li, Teng, et al.
Publicado: (2016)

LUBAC controls chromosome alignment by targeting CENP-E to attached kinetochores
por: Wu, Min, et al.
Publicado: (2019)

The Kinetochore Protein Kis1/Eic1/Mis19 Ensures the Integrity of Mitotic Spindles through Maintenance of Kinetochore Factors Mis6/CENP-I and CENP-A
por: Hirai, Hayato, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_9gmh6mpjbi2344ec5heqke6qqr