A highly conserved SOX6 double binding site mediates SOX6 gene downregulation in erythroid cells

The Sox6 transcription factor plays critical roles in various cell types, including erythroid cells. Sox6-deficient mice are anemic due to impaired red cell maturation and show inappropriate globin gene expression in definitive erythrocytes. To identify new Sox6 target genes in erythroid cells, we u...

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Detalles Bibliográficos
Autores principales: Cantu', Claudio, Grande, Vito, Alborelli, Ilaria, Cassinelli, Letizia, Cantu’, Ileana, Colzani, Maria Teresa, Ierardi, Rossella, Ronzoni, Luisa, Cappellini, Maria Domenica, Ferrari, Giuliana, Ottolenghi, Sergio, Ronchi, Antonella
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025548/
https://www.ncbi.nlm.nih.gov/pubmed/20852263
http://dx.doi.org/10.1093/nar/gkq819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025548/
https://www.ncbi.nlm.nih.gov/pubmed/20852263
http://dx.doi.org/10.1093/nar/gkq819

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