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A highly conserved SOX6 double binding site mediates SOX6 gene downregulation in erythroid cells
The Sox6 transcription factor plays critical roles in various cell types, including erythroid cells. Sox6-deficient mice are anemic due to impaired red cell maturation and show inappropriate globin gene expression in definitive erythrocytes. To identify new Sox6 target genes in erythroid cells, we u...
Autores principales: | Cantu', Claudio, Grande, Vito, Alborelli, Ilaria, Cassinelli, Letizia, Cantu’, Ileana, Colzani, Maria Teresa, Ierardi, Rossella, Ronzoni, Luisa, Cappellini, Maria Domenica, Ferrari, Giuliana, Ottolenghi, Sergio, Ronchi, Antonella |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025548/ https://www.ncbi.nlm.nih.gov/pubmed/20852263 http://dx.doi.org/10.1093/nar/gkq819 |
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