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p53 activates the PANK1/miRNA-107 gene leading to downregulation of CDK6 and p130 cell cycle proteins

The tumor suppressor p53 is a central regulator of cell-cycle arrest and apoptosis by acting as a transcription factor to regulate numerous genes. We identified all human p53-regulated mRNAs by microarray analyses and searched for protein-coding genes which contain intronic miRNAs. Among others, thi...

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Detalles Bibliográficos
Autores principales:	Böhlig, Levin, Friedrich, Maik, Engeland, Kurt
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Gene Regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025554/ https://www.ncbi.nlm.nih.gov/pubmed/20833636 http://dx.doi.org/10.1093/nar/gkq796

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