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DNA is a co-factor for its own replication in Xenopus egg extracts

Soluble Xenopus egg extracts efficiently replicate added plasmids using a physiological mechanism, and thus represent a powerful system to understand vertebrate DNA replication. Surprisingly, DNA replication in this system is highly sensitive to plasmid concentration, being undetectable below ∼10 pM...

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Detalles Bibliográficos
Autores principales:	Lebofsky, Ronald, van Oijen, Antoine M., Walter, Johannes C.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025559/ https://www.ncbi.nlm.nih.gov/pubmed/20861001 http://dx.doi.org/10.1093/nar/gkq739

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