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Dissecting endonuclease and exonuclease activities in endonuclease V from Thermotoga maritima
Endonuclease V is an enzyme that initiates a conserved DNA repair pathway by making an endonucleolytic incision at the 3′-side 1 nt from a deaminated base lesion. DNA cleavage analysis using mutants defective in DNA binding and Mn(2+) as a metal cofactor reveals a novel 3′-exonuclease activity in en...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025561/ https://www.ncbi.nlm.nih.gov/pubmed/20852258 http://dx.doi.org/10.1093/nar/gkq791 |