mRNA degradation controls differentiation state-dependent differences in transcript and splice variant abundance

Expression profiling experiments usually provide a static snapshot of messenger RNA (mRNA) levels. Improved understanding of the dynamics of mRNA synthesis and degradation will aid the development of sound bioinformatic models for control of gene expression. We studied mRNA stability in proliferatin...

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Detalles Bibliográficos
Autores principales: 't Hoen, Peter A. C., Hirsch, Michael, de Meijer, Emile J., de Menezes, Renée X., van Ommen, Gert Jan, den Dunnen, Johan T.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025562/
https://www.ncbi.nlm.nih.gov/pubmed/20852259
http://dx.doi.org/10.1093/nar/gkq790

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