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Complementary non-radioactive assays for investigation of human flap endonuclease 1 activity
FEN1, a key participant in DNA replication and repair, is the major human flap endonuclease that recognizes and cleaves flap DNA structures. Deficiencies in FEN1 function or deletion of the fen1 gene have profound biological effects, including the suppression of repair of DNA damage incurred from th...
Autores principales: | Dorjsuren, Dorjbal, Kim, Daemyung, Maloney, David J., Wilson, David M., Simeonov, Anton |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025571/ https://www.ncbi.nlm.nih.gov/pubmed/21062821 http://dx.doi.org/10.1093/nar/gkq1082 |
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