Cargando…

High-level expression by tissue/cancer-specific promoter with strict specificity using a single-adenoviral vector

Tissue-/cancer-specific promoters for use in adenovirus vectors (AdVs) are valuable for elucidating specific gene functions and for use in gene therapy. However, low activity, non-specific expression and size limitations in the vector are always problems. Here, we developed a ‘double-unit’ AdV conta...

Descripción completa

Detalles Bibliográficos
Autores principales: Kanegae, Yumi, Terashima, Miho, Kondo, Saki, Fukuda, Hiromitsu, Maekawa, Aya, Pei, Zheng, Saito, Izumu
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025582/
https://www.ncbi.nlm.nih.gov/pubmed/21051352
http://dx.doi.org/10.1093/nar/gkq966