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Novel free paclitaxel-loaded poly(L-γ-glutamylglutamine)–paclitaxel nanoparticles

The purpose of this study was to develop a novel formulation of paclitaxel (PTX) that would improve its therapeutic index. Here, we combined a concept of polymer–PTX drug conjugate with a concept of polymeric micelle drug delivery to form novel free PTX-loaded poly(L-γ-glutamylglutamine) (PGG)–PTX c...

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Detalles Bibliográficos
Autores principales:	Yang, Danbo, Van, Sang, Jiang, Xinguo, Yu, Lei
Formato:	Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2011
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025592/ https://www.ncbi.nlm.nih.gov/pubmed/21289985 http://dx.doi.org/10.2147/IJN.S15839

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