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Targeting choroid plexus epithelia and ventricular ependyma for drug delivery to the central nervous system

BACKGROUND: Because the choroid plexus (CP) is uniquely suited to control the composition of cerebrospinal fluid (CSF), there may be therapeutic benefits to increasing the levels of biologically active proteins in CSF to modulate central nervous system (CNS) functions. To this end, we sought to iden...

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Detalles Bibliográficos
Autores principales: Gonzalez, Ana Maria, Leadbeater, Wendy E, Burg, Michael, Sims, Karen, Terasaki, Tetsuya, Johanson, Conrad E, Stopa, Edward G, Eliceiri, Brian P, Baird, Andrew
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025905/
https://www.ncbi.nlm.nih.gov/pubmed/21214926
http://dx.doi.org/10.1186/1471-2202-12-4