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Single-Nucleotide Polymorphisms in LPA Explain Most of the Ancestry-Specific Variation in Lp(a) Levels in African Americans
Lipoprotein(a) (Lp(a)) is an important causal cardiovascular risk factor, with serum Lp(a) levels predicting atherosclerotic heart disease and genetic determinants of Lp(a) levels showing association with myocardial infarction. Lp(a) levels vary widely between populations, with African-derived popul...
Autores principales: | Deo, Rahul C., Wilson, James G., Xing, Chao, Lawson, Kim, Kao, W. H. Linda, Reich, David, Tandon, Arti, Akylbekova, Ermeg, Patterson, Nick, Mosley, Thomas H., Boerwinkle, Eric, Taylor, Herman A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025914/ https://www.ncbi.nlm.nih.gov/pubmed/21283670 http://dx.doi.org/10.1371/journal.pone.0014581 |
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