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Identification of novel DNA methylation inhibitors via a two-component reporter gene system

BACKGROUND: Targeting abnormal DNA methylation represents a therapeutically relevant strategy for cancer treatment as demonstrated by the US Food and Drug Administration approval of the DNA methyltransferase inhibitors azacytidine and 5-aza-2'-deoxycytidine for the treatment of myelodysplastic...

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Detalles Bibliográficos
Autores principales:	Lin, Yi-Shiuan, Shaw, Arthur Y, Wang, Shi-Gang, Hsu, Chia-Chen, Teng, I-Wen, Tseng, Min-Jen, Huang, Tim HM, Chen, Ching-Shih, Leu, Yu-Wei, Hsiao, Shu-Huei
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025941/ https://www.ncbi.nlm.nih.gov/pubmed/21219604 http://dx.doi.org/10.1186/1423-0127-18-3

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