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Global analysis of estrogen receptor beta binding to breast cancer cell genome reveals an extensive interplay with estrogen receptor alpha for target gene regulation

BACKGROUND: Estrogen receptors alpha (ERα) and beta (ERβ) are transcription factors (TFs) that mediate estrogen signaling and define the hormone-responsive phenotype of breast cancer (BC). The two receptors can be found co-expressed and play specific, often opposite, roles, with ERβ being able to mo...

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Detalles Bibliográficos
Autores principales: Grober, Oli MV, Mutarelli, Margherita, Giurato, Giorgio, Ravo, Maria, Cicatiello, Luigi, De Filippo, Maria Rosaria, Ferraro, Lorenzo, Nassa, Giovanni, Papa, Maria Francesca, Paris, Ornella, Tarallo, Roberta, Luo, Shujun, Schroth, Gary P, Benes, Vladimir, Weisz, Alessandro
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025958/
https://www.ncbi.nlm.nih.gov/pubmed/21235772
http://dx.doi.org/10.1186/1471-2164-12-36

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