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A human ribonuclease induces apoptosis associated with p21(WAF1/CIP1 )induction and JNK inactivation

BACKGROUND: Ribonucleases are promising agents for use in anticancer therapy. Among the different ribonucleases described to be cytotoxic, a paradigmatic example is onconase which manifests cytotoxic and cytostatic effects, presents synergism with several kinds of anticancer drugs and is currently i...

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Detalles Bibliográficos
Autores principales:	Castro, Jessica, Ribó, Marc, Navarro, Susanna, Nogués, Maria Victòria, Vilanova, Maria, Benito, Antoni
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025972/ https://www.ncbi.nlm.nih.gov/pubmed/21223552 http://dx.doi.org/10.1186/1471-2407-11-9

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