Cargando…
Vectors Based on Modified Vaccinia Ankara Expressing Influenza H5N1 Hemagglutinin Induce Substantial Cross-Clade Protective Immunity
BACKGROUND: New highly pathogenic H5N1 influenza viruses are continuing to evolve with a potential threat for an influenza pandemic. So far, the H5N1 influenza viruses have not widely circulated in humans and therefore constitute a high risk for the non immune population. The aim of this study was t...
Autores principales: | Hessel, Annett, Schwendinger, Michael, Holzer, Georg W., Orlinger, Klaus K., Coulibaly, Sogue, Savidis-Dacho, Helga, Zips, Marie-Luise, Crowe, Brian A., Kreil, Thomas R., Ehrlich, Hartmut J., Barrett, P. Noel, Falkner, Falko G. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026016/ https://www.ncbi.nlm.nih.gov/pubmed/21283631 http://dx.doi.org/10.1371/journal.pone.0016247 |
Ejemplares similares
-
A Pandemic Influenza H1N1 Live Vaccine Based on Modified Vaccinia Ankara Is Highly Immunogenic and Protects Mice in Active and Passive Immunizations
por: Hessel, Annett, et al.
Publicado: (2010) -
MVA Vectors Expressing Conserved Influenza Proteins Protect Mice against Lethal Challenge with H5N1, H9N2 and H7N1 Viruses
por: Hessel, Annett, et al.
Publicado: (2014) -
Pre-Clinical Efficacy and Safety of Experimental Vaccines Based on Non-Replicating Vaccinia Vectors against Yellow Fever
por: Schäfer, Birgit, et al.
Publicado: (2011) -
A Whole Virus Pandemic Influenza H1N1 Vaccine Is Highly Immunogenic and Protective in Active Immunization and Passive Protection Mouse Models
por: Kistner, Otfried, et al.
Publicado: (2010) -
A modified vaccinia Ankara vaccine vector expressing a mosaic H5 hemagglutinin reduces viral shedding in rhesus macaques
por: Florek, Kelsey R., et al.
Publicado: (2017)