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Genome-Wide Analysis of PDZ Domain Binding Reveals Inherent Functional Overlap within the PDZ Interaction Network

Binding selectivity and cross-reactivity within one of the largest and most abundant interaction domain families, the PDZ family, has long been enigmatic. The complete human PDZ domain complement (the PDZome) consists of 267 domains and we applied here a Bayesian selectivity model to predict hundred...

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Detalles Bibliográficos
Autores principales:	te Velthuis, Aartjan J. W., Sakalis, Philippe A., Fowler, Donald A., Bagowski, Christoph P.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026046/ https://www.ncbi.nlm.nih.gov/pubmed/21283644 http://dx.doi.org/10.1371/journal.pone.0016047

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