Applying internal coordinate mechanics to model the interactions between 8R-lipoxygenase and its substrate

BACKGROUND: Lipoxygenases (LOX) play pivotal roles in the biosynthesis of leukotrienes and other biologically active potent signalling compounds. Developing inhibitors for LOX is of high interest to researchers. Modelling the interactions between LOX and its substrate arachidonic acid is critical fo...

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Detalles Bibliográficos
Autores principales: Bai, Shuju, Du, Tianchuan, Khosravi, Ebrahim
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026367/
https://www.ncbi.nlm.nih.gov/pubmed/20946603
http://dx.doi.org/10.1186/1471-2105-11-S6-S2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026367/
https://www.ncbi.nlm.nih.gov/pubmed/20946603
http://dx.doi.org/10.1186/1471-2105-11-S6-S2

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