Cargando…
IView: introgression library visualization and query tool
BACKGROUND: An introgression library is a family of near-isogenic lines in a common genetic background, each of which carries one or more genomic regions contributed by a donor genome. Near-isogenic lines are powerful genetic resources for the analysis of phenotypic variation and are important for m...
Autores principales: | , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026375/ https://www.ncbi.nlm.nih.gov/pubmed/20946612 http://dx.doi.org/10.1186/1471-2105-11-S6-S28 |
_version_ | 1782197038546419712 |
---|---|
author | Bottoms, Christopher A Flint-Garcia, Sherry McMullen, Michael D |
author_facet | Bottoms, Christopher A Flint-Garcia, Sherry McMullen, Michael D |
author_sort | Bottoms, Christopher A |
collection | PubMed |
description | BACKGROUND: An introgression library is a family of near-isogenic lines in a common genetic background, each of which carries one or more genomic regions contributed by a donor genome. Near-isogenic lines are powerful genetic resources for the analysis of phenotypic variation and are important for map-base cloning genes underlying mutations and traits. With many thousands of distinct genotypes, querying introgression libraries for lines of interest is an issue. RESULTS: We have created IView, a tool to graphically display and query near-isogenic line libraries for specific introgressions. This tool incorporates a web interface for displaying the location and extent of introgressions. Each genetic marker is associated with a position on a reference map. Users can search for introgressions using marker names, or chromosome number and map positions. This search results in a display of lines carrying an introgression at the specified position. Upon selecting one of the lines, color-coded introgressions on all chromosomes of the line are displayed graphically. The source code for IView can be downloaded from http://xrl.us/iview. CONCLUSIONS: IView will be useful for those wanting to make introgression data from their stock of germplasm searchable. |
format | Text |
id | pubmed-3026375 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-30263752011-01-26 IView: introgression library visualization and query tool Bottoms, Christopher A Flint-Garcia, Sherry McMullen, Michael D BMC Bioinformatics Proceedings BACKGROUND: An introgression library is a family of near-isogenic lines in a common genetic background, each of which carries one or more genomic regions contributed by a donor genome. Near-isogenic lines are powerful genetic resources for the analysis of phenotypic variation and are important for map-base cloning genes underlying mutations and traits. With many thousands of distinct genotypes, querying introgression libraries for lines of interest is an issue. RESULTS: We have created IView, a tool to graphically display and query near-isogenic line libraries for specific introgressions. This tool incorporates a web interface for displaying the location and extent of introgressions. Each genetic marker is associated with a position on a reference map. Users can search for introgressions using marker names, or chromosome number and map positions. This search results in a display of lines carrying an introgression at the specified position. Upon selecting one of the lines, color-coded introgressions on all chromosomes of the line are displayed graphically. The source code for IView can be downloaded from http://xrl.us/iview. CONCLUSIONS: IView will be useful for those wanting to make introgression data from their stock of germplasm searchable. BioMed Central 2010-10-07 /pmc/articles/PMC3026375/ /pubmed/20946612 http://dx.doi.org/10.1186/1471-2105-11-S6-S28 Text en Copyright ©2010 Bottoms et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Proceedings Bottoms, Christopher A Flint-Garcia, Sherry McMullen, Michael D IView: introgression library visualization and query tool |
title | IView: introgression library visualization and query tool |
title_full | IView: introgression library visualization and query tool |
title_fullStr | IView: introgression library visualization and query tool |
title_full_unstemmed | IView: introgression library visualization and query tool |
title_short | IView: introgression library visualization and query tool |
title_sort | iview: introgression library visualization and query tool |
topic | Proceedings |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026375/ https://www.ncbi.nlm.nih.gov/pubmed/20946612 http://dx.doi.org/10.1186/1471-2105-11-S6-S28 |
work_keys_str_mv | AT bottomschristophera iviewintrogressionlibraryvisualizationandquerytool AT flintgarciasherry iviewintrogressionlibraryvisualizationandquerytool AT mcmullenmichaeld iviewintrogressionlibraryvisualizationandquerytool |