Experimental Models of Abdominal Aortic Aneurysms

Despite being a leading cause of death in the West, the pathophysiology of abdominal aortic aneurysms (AAA) is still incompletely understood. Pharmacotherapy to reduce the growth of small AAAs is limited and techniques for repairing aneurysms continue to evolve. Experimental models play a key role i...

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Detalles Bibliográficos
Autor principal: Tsui, Janice C
Formato: Texto
Lenguaje:English
Publicado: Bentham Open 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026392/
https://www.ncbi.nlm.nih.gov/pubmed/21270944
http://dx.doi.org/10.2174/1874192401004010221
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author Tsui, Janice C
author_facet Tsui, Janice C
author_sort Tsui, Janice C
collection PubMed
description Despite being a leading cause of death in the West, the pathophysiology of abdominal aortic aneurysms (AAA) is still incompletely understood. Pharmacotherapy to reduce the growth of small AAAs is limited and techniques for repairing aneurysms continue to evolve. Experimental models play a key role in AAA research, as they allow a detailed evaluation of the pathogenesis of disease progression. This review focuses on in vivo experimental models, which have improved our understanding of the potential mechanisms of AAA development and contributed to the advancement of new treatments.
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spelling pubmed-30263922011-01-26 Experimental Models of Abdominal Aortic Aneurysms Tsui, Janice C Open Cardiovasc Med J Article Despite being a leading cause of death in the West, the pathophysiology of abdominal aortic aneurysms (AAA) is still incompletely understood. Pharmacotherapy to reduce the growth of small AAAs is limited and techniques for repairing aneurysms continue to evolve. Experimental models play a key role in AAA research, as they allow a detailed evaluation of the pathogenesis of disease progression. This review focuses on in vivo experimental models, which have improved our understanding of the potential mechanisms of AAA development and contributed to the advancement of new treatments. Bentham Open 2010-11-26 /pmc/articles/PMC3026392/ /pubmed/21270944 http://dx.doi.org/10.2174/1874192401004010221 Text en © Janice C. Tsui; Licensee Bentham Open. http://creativecommons.org/licenses/by-nc/3.0/ This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
spellingShingle Article
Tsui, Janice C
Experimental Models of Abdominal Aortic Aneurysms
title Experimental Models of Abdominal Aortic Aneurysms
title_full Experimental Models of Abdominal Aortic Aneurysms
title_fullStr Experimental Models of Abdominal Aortic Aneurysms
title_full_unstemmed Experimental Models of Abdominal Aortic Aneurysms
title_short Experimental Models of Abdominal Aortic Aneurysms
title_sort experimental models of abdominal aortic aneurysms
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026392/
https://www.ncbi.nlm.nih.gov/pubmed/21270944
http://dx.doi.org/10.2174/1874192401004010221
work_keys_str_mv AT tsuijanicec experimentalmodelsofabdominalaorticaneurysms

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