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Ro 15-4513 Antagonizes Alcohol-Induced Sedation in Mice Through αβγ2-type GABA(A) Receptors
Ethyl alcohol (ethanol) has many molecular targets in the nervous system, its potency at these sites being low compared to those of sedative drugs. This has made it difficult to discover ethanol's binding site(s). There are two putative binding sites at γ-aminobutyric acid (GABA) type A recepto...
Autores principales: | Linden, Anni-Maija, Schmitt, Ulrich, Leppä, Elli, Wulff, Peer, Wisden, William, Lüddens, Hartmut, Korpi, Esa R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026482/ https://www.ncbi.nlm.nih.gov/pubmed/21270945 http://dx.doi.org/10.3389/fnins.2011.00003 |
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