Modeling complex neuropsychiatric disease with induced pluripotent stem cells

The study of neuropsychiatric diseases and the development of effective treatments have been limited by a lack of appropriate models. Induced pluripotent stem cells (iPSCs) represent a potentially limitless supply of patient-specific cells for the study of neuropsychiatric disorders. In this review,...

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Detalles Bibliográficos
Autores principales: Ross, P Joel, Ellis, James
Formato: Texto
Lenguaje:English
Publicado: Faculty of 1000 Ltd 2010
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026614/
https://www.ncbi.nlm.nih.gov/pubmed/21283649
http://dx.doi.org/10.3410/B2-84
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author Ross, P Joel
Ellis, James
author_facet Ross, P Joel
Ellis, James
author_sort Ross, P Joel
collection PubMed
description The study of neuropsychiatric diseases and the development of effective treatments have been limited by a lack of appropriate models. Induced pluripotent stem cells (iPSCs) represent a potentially limitless supply of patient-specific cells for the study of neuropsychiatric disorders. In this review, we will discuss the potential and limitations of iPSCs for the development of cell-based models of neuropsychiatric diseases and the identification of novel therapeutics.
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spelling pubmed-30266142011-01-31 Modeling complex neuropsychiatric disease with induced pluripotent stem cells Ross, P Joel Ellis, James F1000 Biol Rep Review Article The study of neuropsychiatric diseases and the development of effective treatments have been limited by a lack of appropriate models. Induced pluripotent stem cells (iPSCs) represent a potentially limitless supply of patient-specific cells for the study of neuropsychiatric disorders. In this review, we will discuss the potential and limitations of iPSCs for the development of cell-based models of neuropsychiatric diseases and the identification of novel therapeutics. Faculty of 1000 Ltd 2010-12-08 /pmc/articles/PMC3026614/ /pubmed/21283649 http://dx.doi.org/10.3410/B2-84 Text en © 2010 Faculty of 1000 Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes
spellingShingle Review Article
Ross, P Joel
Ellis, James
Modeling complex neuropsychiatric disease with induced pluripotent stem cells
title Modeling complex neuropsychiatric disease with induced pluripotent stem cells
title_full Modeling complex neuropsychiatric disease with induced pluripotent stem cells
title_fullStr Modeling complex neuropsychiatric disease with induced pluripotent stem cells
title_full_unstemmed Modeling complex neuropsychiatric disease with induced pluripotent stem cells
title_short Modeling complex neuropsychiatric disease with induced pluripotent stem cells
title_sort modeling complex neuropsychiatric disease with induced pluripotent stem cells
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026614/
https://www.ncbi.nlm.nih.gov/pubmed/21283649
http://dx.doi.org/10.3410/B2-84
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