Use of dexmedetomidine for pain control

For many years, clonidine, an α2-adrenergic receptor (α2-AR) agonist, has been widely used as an analgesic adjuvant in perioperative conditions and pain therapy. Dexmedetomidine (DMET) is currently the most potent α2-AR agonist available and was first approved as a sedative agent for use in the inte...

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Detalles Bibliográficos
Autores principales: Grosu, Irina, Lavand'homme, Patricia
Formato: Texto
Lenguaje:English
Publicado: Faculty of 1000 Ltd 2010
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026617/
https://www.ncbi.nlm.nih.gov/pubmed/21283652
http://dx.doi.org/10.3410/M2-90
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author Grosu, Irina
Lavand'homme, Patricia
author_facet Grosu, Irina
Lavand'homme, Patricia
author_sort Grosu, Irina
collection PubMed
description For many years, clonidine, an α2-adrenergic receptor (α2-AR) agonist, has been widely used as an analgesic adjuvant in perioperative conditions and pain therapy. Dexmedetomidine (DMET) is currently the most potent α2-AR agonist available and was first approved as a sedative agent for use in the intensive care unit. However, DMET has recently been investigated for its analgesic effects and has the potential to become an alternative to clonidine.
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spelling pubmed-30266172011-01-31 Use of dexmedetomidine for pain control Grosu, Irina Lavand'homme, Patricia F1000 Med Rep Review Article For many years, clonidine, an α2-adrenergic receptor (α2-AR) agonist, has been widely used as an analgesic adjuvant in perioperative conditions and pain therapy. Dexmedetomidine (DMET) is currently the most potent α2-AR agonist available and was first approved as a sedative agent for use in the intensive care unit. However, DMET has recently been investigated for its analgesic effects and has the potential to become an alternative to clonidine. Faculty of 1000 Ltd 2010-12-17 /pmc/articles/PMC3026617/ /pubmed/21283652 http://dx.doi.org/10.3410/M2-90 Text en © 2010 Faculty of 1000 Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes
spellingShingle Review Article
Grosu, Irina
Lavand'homme, Patricia
Use of dexmedetomidine for pain control
title Use of dexmedetomidine for pain control
title_full Use of dexmedetomidine for pain control
title_fullStr Use of dexmedetomidine for pain control
title_full_unstemmed Use of dexmedetomidine for pain control
title_short Use of dexmedetomidine for pain control
title_sort use of dexmedetomidine for pain control
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026617/
https://www.ncbi.nlm.nih.gov/pubmed/21283652
http://dx.doi.org/10.3410/M2-90
work_keys_str_mv AT grosuirina useofdexmedetomidineforpaincontrol
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