Cargando…

Creating transplant tolerance by taming adverse intragraft innate immunity

Certain forms of inflammation of an allograft are highly detrimental to the induction and maintenance of transplant tolerance as they foster stable commitment to graft-destructive, not graft-protective, forms of T-cell immunity. Hence, a reduction in adverse tissue inflammation may prove crucial in...

Descripción completa

Detalles Bibliográficos
Autores principales: Hanidziar, Dusan, Koulmanda, Maria, Strom, Terry B
Formato: Texto
Lenguaje:English
Publicado: Faculty of 1000 Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026643/
https://www.ncbi.nlm.nih.gov/pubmed/21283601
http://dx.doi.org/10.3410/B2-83
_version_ 1782197062801031168
author Hanidziar, Dusan
Koulmanda, Maria
Strom, Terry B
author_facet Hanidziar, Dusan
Koulmanda, Maria
Strom, Terry B
author_sort Hanidziar, Dusan
collection PubMed
description Certain forms of inflammation of an allograft are highly detrimental to the induction and maintenance of transplant tolerance as they foster stable commitment to graft-destructive, not graft-protective, forms of T-cell immunity. Hence, a reduction in adverse tissue inflammation may prove crucial in facilitating the induction and maintenance of a long-lasting state of transplant tolerance.
format Text
id pubmed-3026643
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher Faculty of 1000 Ltd
record_format MEDLINE/PubMed
spelling pubmed-30266432011-01-31 Creating transplant tolerance by taming adverse intragraft innate immunity Hanidziar, Dusan Koulmanda, Maria Strom, Terry B F1000 Biol Rep Review Article Certain forms of inflammation of an allograft are highly detrimental to the induction and maintenance of transplant tolerance as they foster stable commitment to graft-destructive, not graft-protective, forms of T-cell immunity. Hence, a reduction in adverse tissue inflammation may prove crucial in facilitating the induction and maintenance of a long-lasting state of transplant tolerance. Faculty of 1000 Ltd 2010-11-24 /pmc/articles/PMC3026643/ /pubmed/21283601 http://dx.doi.org/10.3410/B2-83 Text en © 2010 Faculty of 1000 Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes
spellingShingle Review Article
Hanidziar, Dusan
Koulmanda, Maria
Strom, Terry B
Creating transplant tolerance by taming adverse intragraft innate immunity
title Creating transplant tolerance by taming adverse intragraft innate immunity
title_full Creating transplant tolerance by taming adverse intragraft innate immunity
title_fullStr Creating transplant tolerance by taming adverse intragraft innate immunity
title_full_unstemmed Creating transplant tolerance by taming adverse intragraft innate immunity
title_short Creating transplant tolerance by taming adverse intragraft innate immunity
title_sort creating transplant tolerance by taming adverse intragraft innate immunity
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026643/
https://www.ncbi.nlm.nih.gov/pubmed/21283601
http://dx.doi.org/10.3410/B2-83
work_keys_str_mv AT hanidziardusan creatingtransplanttolerancebytamingadverseintragraftinnateimmunity
AT koulmandamaria creatingtransplanttolerancebytamingadverseintragraftinnateimmunity
AT stromterryb creatingtransplanttolerancebytamingadverseintragraftinnateimmunity