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Does GSK-3 provide a shortcut for PI3K activation of Wnt signalling?
Glycogen synthase kinase-3 (GSK-3) is a well-established downstream component of the phosphatidylinositol 3-kinase (PI3K) signalling pathway but is also a key enzyme in negatively regulating the canonical Wnt/β-catenin signalling pathway. Several recent studies argue that PKB (protein kinase B)-medi...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Faculty of 1000 Ltd
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026644/ https://www.ncbi.nlm.nih.gov/pubmed/21283602 http://dx.doi.org/10.3410/B2-82 |