Cargando…

Genome-wide joint SNP and CNV analysis of aortic root diameter in African Americans: the HyperGEN study

BACKGROUND: Aortic root diameter is a clinically relevant trait due to its known relationship with the pathogenesis of aortic regurgitation and risk for aortic dissection. African Americans are an understudied population despite a particularly high burden of cardiovascular diseases. We report a geno...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wineinger, Nathan E, Patki, Amit, Meyers, Kristin J, Broeckel, Ulrich, Gu, Charles C, Rao, DC, Devereux, Richard B, Arnett, Donna K, Tiwari, Hemant K
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3027088/ https://www.ncbi.nlm.nih.gov/pubmed/21223598 http://dx.doi.org/10.1186/1755-8794-4-4

Ejemplares similares

Copy number variations associated with obesity related traits in African Americans: a joint analysis between GENOA and HyperGEN
por: Zhao, Wei, et al.
Publicado: (2012)

A 6-CpG validated methylation risk score model for metabolic syndrome: The HyperGEN and GOLDN studies
por: Hidalgo, Bertha A., et al.
Publicado: (2021)

The role of SNP-loop diuretic interactions in hypertension across ethnic groups in HyperGEN
por: de Las Fuentes, Lisa, et al.
Publicado: (2013)

PCSK9 variation and association with blood pressure in African Americans: preliminary findings from the HyperGEN and REGARDS studies
por: Tran, Ngan T., et al.
Publicado: (2015)

Genome-Wide Detection of Allele Specific Copy Number Variation Associated with Insulin Resistance in African Americans from the HyperGEN Study
por: Irvin, Marguerite R., et al.
Publicado: (2011)

Differentially Methylated DNA Regions and Left Ventricular Hypertrophy in African Americans: A HyperGEN Study
por: Jones, Alana C., et al.
Publicado: (2022)

An evaluation of the metabolic syndrome in the HyperGEN study
por: Kraja, Aldi T, et al.
Publicado: (2005)

Genome-wide association study identifies single-nucleotide polymorphism in KCNB1 associated with left ventricular mass in humans: The HyperGEN Study
por: Arnett, Donna K, et al.
Publicado: (2009)

Epistatic effects of ACE I/D and AGT gene variants on left ventricular mass in hypertensive patients: The HyperGEN Study
por: Lynch, Amy I., et al.
Publicado: (2011)

Association of Comorbidity Burden With Abnormal Cardiac Mechanics: Findings From the HyperGEN Study
por: Selvaraj, Senthil, et al.
Publicado: (2014)

An investigation of the effects of lipid-lowering medications: genome-wide linkage analysis of lipids in the HyperGEN study
por: Wu, Jun, et al.
Publicado: (2007)

Identification of a pleiotropic locus on chromosome 7q for a composite left ventricular wall thickness factor and body mass index: the HyperGEN Study
por: Tang, Weihong, et al.
Publicado: (2009)

AGT M235T Genotype/Anxiety Interaction and Gender in the HyperGEN Study
por: Knox, Sarah S., et al.
Publicado: (2010)

Boundary value problems for hypergenic function vectors
por: Zhang, Guiling, et al.
Publicado: (2018)

AutoCNV: a semiautomatic CNV interpretation system based on the 2019 ACMG/ClinGen Technical Standards for CNVs
por: Fan, Chunna, et al.
Publicado: (2021)

Effect of Combining Multiple CNV Defining Algorithms on the Reliability of CNV Calls from SNP Genotyping Data
por: Kim, Soon-Young, et al.
Publicado: (2012)

Whole genome sequencing of simmental cattle for SNP and CNV discovery
por: Sun, Ting, et al.
Publicado: (2023)

A clustering analysis of lipoprotein diameters in the metabolic syndrome
por: Frazier-Wood, Alexis C, et al.
Publicado: (2011)

GStream: Improving SNP and CNV Coverage on Genome-Wide Association Studies
por: Alonso, Arnald, et al.
Publicado: (2013)

Longevity and Plasticity of CFTR Provide an Argument for Noncanonical SNP Organization in Hominid DNA
por: Hill, Aubrey E., et al.
Publicado: (2014)

Whole genome resequencing of black Angus and Holstein cattle for SNP and CNV discovery
por: Stothard, Paul, et al.
Publicado: (2011)

Genomic Variations Explorer (GenVarX): a toolset for annotating promoter and CNV regions using genotypic and phenotypic differences
por: Chan, Yen On, et al.
Publicado: (2023)

The Impact of Errors in Copy Number Variation Detection Algorithms on Association Results
por: Wineinger, Nathan E., et al.
Publicado: (2012)

Lipoprotein Lipase S447X variant associated with VLDL, LDL and HDL diameter clustering in the MetS
por: Wood, Alexis C, et al.
Publicado: (2011)

Epigenome-wide association study of metabolic syndrome in African-American adults
por: Akinyemiju, Tomi, et al.
Publicado: (2018)

The effects of angiotensinogen gene polymorphisms on cardiovascular disease outcomes during antihypertensive treatment in the GenHAT study
por: Do, Anh N., et al.
Publicado: (2014)

A sequential Monte Carlo framework for haplotype inference in CNV/SNP genotype data
por: Iliadis, Alexandros, et al.
Publicado: (2014)

cnvScan: a CNV screening and annotation tool to improve the clinical utility of computational CNV prediction from exome sequencing data
por: Samarakoon, Pubudu Saneth, et al.
Publicado: (2016)

RPE disruption and hyper-transmission are early signs of secondary CNV with punctate inner choroidopathy in structure-OCT
por: Chen, Yanru, et al.
Publicado: (2021)

The effects of genes implicated in cardiovascular disease on blood-pressure response to treatment among treatment-naïve hypertensive African Americans in the GenHAT study
por: Do, Anh N, et al.
Publicado: (2016)

Metabolite profiles and DNA methylation in metabolic syndrome: a two-sample, bidirectional Mendelian randomization
por: Jones, Alana C., et al.
Publicado: (2023)

The complex SNP and CNV genetic architecture of the increased risk of congenital heart defects in Down syndrome
por: Sailani, M. Reza, et al.
Publicado: (2013)

Combined Analysis of SNP Array Data Identifies Novel CNV Candidates and Pathways in Ependymoma and Mesothelioma
por: Wajnberg, Gabriel, et al.
Publicado: (2015)

Integrated CNV-seq, karyotyping and SNP-array analyses for effective prenatal diagnosis of chromosomal mosaicism
por: Ma, Na, et al.
Publicado: (2021)

A Method to Assess Linkage Disequilibrium between CNVs and SNPs Inside Copy Number Variable Regions
por: Wineinger, Nathan E., et al.
Publicado: (2011)

CNV-WebStore: Online CNV Analysis, Storage and Interpretation
por: Vandeweyer, Geert, et al.
Publicado: (2011)

Genetic Contributors of Incident Stroke in 10,700 African Americans With Hypertension: A Meta-Analysis From the Genetics of Hypertension Associated Treatments and Reasons for Geographic and Racial Differences in Stroke Studies
por: Armstrong, Nicole D., et al.
Publicado: (2021)

Whole-Exome Sequencing and hiPSC Cardiomyocyte Models Identify MYRIP, TRAPPC11, and SLC27A6 of Potential Importance to Left Ventricular Hypertrophy in an African Ancestry Population
por: Irvin, Marguerite R., et al.
Publicado: (2021)

Gender differences in CNV burden do not confound schizophrenia CNV associations
por: Han, Jun, et al.
Publicado: (2016)

On the association of common and rare genetic variation influencing body mass index: a combined SNP and CNV analysis
por: Peterson, Roseann E, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_lal8jtrnllk5ufmcn3vq6io2oh