Cargando…

Malignant Pigmented Villonodular Synovitis in the Knee - Report of a Case with Rapid Clinical Progression

Malignant pigmented villonodular synovitis (PVNS) (or malignant giant cell tumor of tendon sheath (GCTTS) is an extremely rare condition defined as a malignant lesion occurring with concomitant or previously documented PVNS at the same site. To date, only less than 20 cases have been reported in Eng...

Descripción completa

Detalles Bibliográficos
Autores principales: Imakiire, Naoaki, Fujino, Takashi, Morii, Takeshi, Honya, Keita, Mochizuki, Kazuo, Satomi, Kazuhiko, Fujioka, Yasunori
Formato: Texto
Lenguaje:English
Publicado: Bentham Open 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3027190/
https://www.ncbi.nlm.nih.gov/pubmed/21270951
http://dx.doi.org/10.2174/1874325001105010013
Descripción
Sumario:Malignant pigmented villonodular synovitis (PVNS) (or malignant giant cell tumor of tendon sheath (GCTTS) is an extremely rare condition defined as a malignant lesion occurring with concomitant or previously documented PVNS at the same site. To date, only less than 20 cases have been reported in English literatures. We report a case of malignant PVNS in the knee in a 56-year-old woman with unpredictable rapid progression. This case raised a caution that when atypical components in specimens of recurrent benign PVNS are detected, even if low-grade or tiny, both pathologists and surgeons should consider the risk of malignant PVNS, which could display aggressive clinical progression.