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LIM kinase1 modulates function of membrane type matrix metalloproteinase 1: implication in invasion of prostate cancer cells

BACKGROUND: LIM kinase 1 (LIMK1) is an actin and microtubule cytoskeleton modulatory protein that is overexpressed in a number of cancerous tissues and cells and also promotes invasion and metastasis of prostate and breast cancer cells. Membrane type matrix metalloproteinase 1 (MT1-MMP) is a critica...

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Detalles Bibliográficos
Autores principales: Tapia, Tenekua, Ottman, Richard, Chakrabarti, Ratna
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3027192/
https://www.ncbi.nlm.nih.gov/pubmed/21219645
http://dx.doi.org/10.1186/1476-4598-10-6