Proteasome Inhibition Represses Unfolded Protein Response and Nox4, Sensitizing Vascular Cells to Endoplasmic Reticulum Stress-Induced Death

BACKGROUND: Endoplasmic reticulum (ER) stress has pathophysiological relevance in vascular diseases and merges with proteasome function. Proteasome inhibition induces cell stress and may have therapeutic implications. However, whether proteasome inhibition potentiates ER stress-induced apoptosis and...

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Detalles Bibliográficos
Autores principales: Amanso, Angélica M., Debbas, Victor, Laurindo, Francisco R. M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3027620/
https://www.ncbi.nlm.nih.gov/pubmed/21297867
http://dx.doi.org/10.1371/journal.pone.0014591

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