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Ablations of Ghrelin and Ghrelin Receptor Exhibit Differential Metabolic Phenotypes and Thermogenic Capacity during Aging
BACKGROUND: Obesity is a hallmark of aging in many Western societies, and is a precursor to numerous serious age-related diseases. Ghrelin (Ghrl), via its receptor (growth hormone secretagogue receptor, GHS-R), is shown to stimulate GH secretion and appetite. Surprisingly, our previous studies showe...
Autores principales: | Ma, Xiaojun, Lin, Ligen, Qin, Guijun, Lu, Xinping, Fiorotto, Marta, Dixit, Vishwa D., Sun, Yuxiang |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3027652/ https://www.ncbi.nlm.nih.gov/pubmed/21298106 http://dx.doi.org/10.1371/journal.pone.0016391 |
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