Cargando…

Effects of Acute Hyperglucagonemia on Hepatic and Intestinal Lipoprotein Production and Clearance in Healthy Humans

OBJECTIVE: The metabolism of hepatic- and intestinally derived lipoproteins is regulated in a complex fashion by nutrients, hormones, and neurologic and other factors. Recent studies in animal models suggest an important role for glucagon acting via the glucagon receptor in regulating hepatic trigly...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiao, Changting, Pavlic, Mirjana, Szeto, Linda, Patterson, Bruce W., Lewis, Gary F.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2011
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028336/ https://www.ncbi.nlm.nih.gov/pubmed/20980459 http://dx.doi.org/10.2337/db10-0763

Ejemplares similares

Insulin Acutely Inhibits Intestinal Lipoprotein Secretion in Humans in Part by Suppressing Plasma Free Fatty Acids
por: Pavlic, Mirjana, et al.
Publicado: (2010)

Evidence That in Uncontrolled Diabetes, Hyperglucagonemia Is Required for Ketosis but Not for Increased Hepatic Glucose Production or Hyperglycemia
por: Meek, Thomas H., et al.
Publicado: (2015)

Sitagliptin, a DPP-4 Inhibitor, Acutely Inhibits Intestinal Lipoprotein Particle Secretion in Healthy Humans
por: Xiao, Changting, et al.
Publicado: (2014)

OR24-4 Targeting Hyperglucagonemia Reverses Glucagon Resistance
por: Bernal-Mizrachi, Ernesto, et al.
Publicado: (2022)

Time-dependent effects of endogenous hyperglucagonemia on glucose homeostasis and hepatic glucagon action
por: Lubaczeuski, Camila, et al.
Publicado: (2023)

GLP-1 and GLP-2 as Yin and Yang of Intestinal Lipoprotein Production: Evidence for Predominance of GLP-2–Stimulated Postprandial Lipemia in Normal and Insulin-Resistant States
por: Hein, Gustavo J., et al.
Publicado: (2013)

Partial Inhibition of Insulin Secretion Results in Glucose Intolerance but Not Hyperglucagonemia
por: Ramanathan, Ranjani P., et al.
Publicado: (2011)

Hyperglucagonemia in Pediatric Adiposity Associates With Cardiometabolic Risk Factors but Not Hyperglycemia
por: Stinson, Sara E, et al.
Publicado: (2022)

Determinants of hyperglucagonemia in pediatric non-alcoholic fatty liver disease
por: Maruszczak, Katharina, et al.
Publicado: (2022)

Association of Basal Hyperglucagonemia with Impaired Glucagon Counterregulation in Type 1 Diabetes
por: Farhy, Leon S., et al.
Publicado: (2012)

Glucagon Resistance and Decreased Susceptibility to Diabetes in a Model of Chronic Hyperglucagonemia
por: Bozadjieva Kramer, Nadejda, et al.
Publicado: (2021)

Control of Blood Glucose in the Absence of Hepatic Glucose Production During Prolonged Fasting in Mice: Induction of Renal and Intestinal Gluconeogenesis by Glucagon
por: Mutel, Elodie, et al.
Publicado: (2011)

Hepatic and Extrahepatic Insulin Clearance Are Differentially Regulated: Results From a Novel Model-Based Analysis of Intravenous Glucose Tolerance Data
por: Polidori, David C., et al.
Publicado: (2016)

Hyperglucagonemia in an animal model of insulin- deficient diabetes: what therapy can improve it?
por: Barbetti, Fabrizio, et al.
Publicado: (2016)

A case of multiple glucagonomas with no clinical manifestations of excess glucagon despite hyperglucagonemia
por: Amano, Shogo, et al.
Publicado: (2023)

Pancreatic α-cell hyperplasia and hyperglucagonemia due to a glucagon receptor splice mutation
por: Larger, Etienne, et al.
Publicado: (2016)

Liver Enzymes Are Associated With Hepatic Insulin Resistance, Insulin Secretion, and Glucagon Concentration in Healthy Men and Women
por: Bonnet, Fabrice, et al.
Publicado: (2011)

Pathways of Glucagon Secretion and Trafficking in the Pancreatic Alpha Cell: Novel Pathways, Proteins, and Targets for Hyperglucagonemia
por: Asadi, Farzad, et al.
Publicado: (2021)

Severity of Diabetes Governs Vascular Lipoprotein Lipase by Affecting Enzyme Dimerization and Disassembly
por: Wang, Ying, et al.
Publicado: (2011)

Delayed clearance of triglyceride‐rich lipoproteins in young, healthy obese subjects
por: Larsen, M. A., et al.
Publicado: (2015)

Central Endocannabinoid Signaling Regulates Hepatic Glucose Production and Systemic Lipolysis
por: O’Hare, James D., et al.
Publicado: (2011)

Increased Hepatic Glucose Production in Fetal Sheep With Intrauterine Growth Restriction Is Not Suppressed by Insulin
por: Thorn, Stephanie R., et al.
Publicado: (2013)

Pseudo‐hyperglucagonemia was observed in pancreatectomized patients when measured by glucagon sandwich enzyme‐linked immunosorbent assay
por: Kobayashi, Masaki, et al.
Publicado: (2020)

Relationship of Abdominal Visceral and Subcutaneous Adipose Tissue With Lipoprotein Particle Number and Size in Type 2 Diabetes
por: Sam, Susan, et al.
Publicado: (2008)

Growth Hormone Control of Hepatic Lipid Metabolism
por: Liu, Zhongbo, et al.
Publicado: (2016)

Pioglitazone Decreases Fasting and Postprandial Endogenous Glucose Production in Proportion to Decrease in Hepatic Triglyceride Content
por: Ravikumar, Balasubramanian, et al.
Publicado: (2008)

The pathophysiology of intestinal lipoprotein production
por: Giammanco, Antonina, et al.
Publicado: (2015)

Pituitary Adenylate Cyclase-Activating Polypeptide Stimulates Glucose Production via the Hepatic Sympathetic Innervation in Rats
por: Yi, Chun-Xia, et al.
Publicado: (2010)

Postabsorptive hyperglucagonemia in patients with type 2 diabetes mellitus analyzed with a novel enzyme‐linked immunosorbent assay
por: Matsuo, Toshihiro, et al.
Publicado: (2015)

The E3 Ubiquitin Ligase IDOL Induces the Degradation of the Low Density Lipoprotein Receptor Family Members VLDLR and ApoER2
por: Hong, Cynthia, et al.
Publicado: (2010)

Propionate Increases Hepatic Pyruvate Cycling and Anaplerosis and Alters Mitochondrial Metabolism
por: Perry, Rachel J., et al.
Publicado: (2016)

Emerging Role of Lymphatics in the Regulation of Intestinal Lipid Mobilization
por: Xiao, Changting, et al.
Publicado: (2020)

Defective Glycogenesis Contributes Toward the Inability to Suppress Hepatic Glucose Production in Response to Hyperglycemia and Hyperinsulinemia in Zucker Diabetic Fatty Rats
por: Torres, Tracy P., et al.
Publicado: (2011)

Acute Administration of Unacylated Ghrelin Has No Effect on Basal or Stimulated Insulin Secretion in Healthy Humans
por: Tong, Jenny, et al.
Publicado: (2014)

Furin-cleaved Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Is Active and Modulates Low Density Lipoprotein Receptor and Serum Cholesterol Levels
por: Lipari, Michael T., et al.
Publicado: (2012)

Yeast culture promotes the production of aged laying hens by improving intestinal digestive enzyme activities and the intestinal health status
por: Zhang, Jia-Cai, et al.
Publicado: (2020)

Hepatic Glucagon Action Is Essential for Exercise-Induced Reversal of Mouse Fatty Liver
por: Berglund, Eric D., et al.
Publicado: (2011)

The relationship among gut microbiota, short-chain fatty acids, and intestinal morphology of growing and healthy broilers
por: Liao, Xiudong, et al.
Publicado: (2020)

Chronic Treatment with the AMP-Kinase Activator AICAR Increases Glycogen Storage and Fatty Acid Oxidation in Skeletal Muscles but Does Not Reduce Hyperglucagonemia and Hyperglycemia in Insulin Deficient Rats
por: Vitzel, Kaio F., et al.
Publicado: (2013)

High-density lipoprotein cholesterol as a predictor of clinical outcomes in patients achieving low-density lipoprotein cholesterol targets with statins after percutaneous coronary intervention
por: Seo, Suk Min, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_8k9nd1re4pd4gm0l4k2ru6hfkg