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Diet-Induced Muscle Insulin Resistance Is Associated With Extracellular Matrix Remodeling and Interaction With Integrin α(2)β(1) in Mice
OBJECTIVE: The hypothesis that high-fat (HF) feeding causes skeletal muscle extracellular matrix (ECM) remodeling in C57BL/6J mice and that this remodeling contributes to diet-induced muscle insulin resistance (IR) through the collagen receptor integrin α(2)β(1) was tested. RESEARCH DESIGN AND METHO...
Autores principales: | Kang, Li, Ayala, Julio E., Lee-Young, Robert S., Zhang, Zhonghua, James, Freyja D., Neufer, P. Darrell, Pozzi, Ambra, Zutter, Mary M., Wasserman, David H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028340/ https://www.ncbi.nlm.nih.gov/pubmed/21270253 http://dx.doi.org/10.2337/db10-1116 |
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