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Diet-Induced Muscle Insulin Resistance Is Associated With Extracellular Matrix Remodeling and Interaction With Integrin α(2)β(1) in Mice

OBJECTIVE: The hypothesis that high-fat (HF) feeding causes skeletal muscle extracellular matrix (ECM) remodeling in C57BL/6J mice and that this remodeling contributes to diet-induced muscle insulin resistance (IR) through the collagen receptor integrin α(2)β(1) was tested. RESEARCH DESIGN AND METHO...

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Detalles Bibliográficos
Autores principales: Kang, Li, Ayala, Julio E., Lee-Young, Robert S., Zhang, Zhonghua, James, Freyja D., Neufer, P. Darrell, Pozzi, Ambra, Zutter, Mary M., Wasserman, David H.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028340/
https://www.ncbi.nlm.nih.gov/pubmed/21270253
http://dx.doi.org/10.2337/db10-1116

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