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Smad3 Deficiency in Mice Protects Against Insulin Resistance and Obesity Induced by a High-Fat Diet

OBJECTIVE: Obesity and associated pathologies are major global health problems. Transforming growth factor-β/Smad3 signaling has been implicated in various metabolic processes, including adipogenesis, insulin expression, and pancreatic β-cell function. However, the systemic effects of Smad3 deficien...

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Detalles Bibliográficos
Autores principales:	Tan, Chek Kun, Leuenberger, Nicolas, Tan, Ming Jie, Yan, Yew Wai, Chen, Yinghui, Kambadur, Ravi, Wahli, Walter, Tan, Nguan Soon
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2011
Materias:	Obesity Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028346/ https://www.ncbi.nlm.nih.gov/pubmed/21270259 http://dx.doi.org/10.2337/db10-0801

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