Frequency and spectrum of mitochondrial 12S rRNA variants in 440 Han Chinese hearing impaired pediatric subjects from two otology clinics

BACKGROUND: Aminoglycoside ototoxicity is one of the common health problems. Mitochondrial 12S rRNA mutations are one of the important causes of aminoglycoside ototoxicity. However, the incidences of 12S rRNA mutations associated with aminoglycoside ototoxicity are less known. METHODS: A total of 44...

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Detalles Bibliográficos
Autores principales: Shen, Zhisen, Zheng, Jing, Chen, Bobei, Peng, Guanghua, Zhang, Ting, Gong, Shasha, Zhu, Yi, Zhang, Chuqin, Li, Ronghua, Yang, Li, Zhou, Jianjin, Cai, Ting, Jin, Lihua, Lu, Jianxin, Guan, Min-Xin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029225/
https://www.ncbi.nlm.nih.gov/pubmed/21205314
http://dx.doi.org/10.1186/1479-5876-9-4

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