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Estimation of Parent Specific DNA Copy Number in Tumors using High-Density Genotyping Arrays
Chromosomal gains and losses comprise an important type of genetic change in tumors, and can now be assayed using microarray hybridization-based experiments. Most current statistical models for DNA copy number estimate total copy number, which do not distinguish between the underlying quantities of...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029233/ https://www.ncbi.nlm.nih.gov/pubmed/21298078 http://dx.doi.org/10.1371/journal.pcbi.1001060 |