Cargando…
Evolutionary Conserved Regulation of HIF-1β by NF-κB
Hypoxia Inducible Factor-1 (HIF-1) is essential for mammalian development and is the principal transcription factor activated by low oxygen tensions. HIF-α subunit quantities and their associated activity are regulated in a post-translational manner, through the concerted action of a class of enzyme...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029248/ https://www.ncbi.nlm.nih.gov/pubmed/21298084 http://dx.doi.org/10.1371/journal.pgen.1001285 |