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Platelet Activating Factor Blocks Interkinetic Nuclear Migration in Retinal Progenitors through an Arrest of the Cell Cycle at the S/G2 Transition

Nuclear migration is regulated by the LIS1 protein, which is the regulatory subunit of platelet activating factor (PAF) acetyl-hydrolase, an enzyme complex that inactivates the lipid mediator PAF. Among other functions, PAF modulates cell proliferation, but its effects upon mechanisms of the cell cy...

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Detalles Bibliográficos
Autores principales: Fragel-Madeira, Lucianne, Meletti, Tamara, Mariante, Rafael M., Monteiro, Robson Q., Einicker-Lamas, Marcelo, Bernardo, Robson R., Lopes, Angela H., Linden, Rafael
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029264/
https://www.ncbi.nlm.nih.gov/pubmed/21298035
http://dx.doi.org/10.1371/journal.pone.0016058