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Prostaglandin E(2) Synthesizing Enzymes in Rheumatoid Arthritis B Cells and the Effects of B Cell Depleting Therapy on Enzyme Expression

INTRODUCTION: B cells may play an important role in promoting immune activation in the rheumatoid synovium and can produce prostaglandin E(2) (PGE(2)) when activated. In its turn, PGE(2) formed by cyclooxygenase (COX) and microsomal prostaglandin E(2) synthase 1 (MPGES1) contributes to the rheumatoi...

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Detalles Bibliográficos
Autores principales:	Gheorghe, Karina Roxana, Thurlings, Rogier M., Westman, Marie, Boumans, Maartje J., Malmström, Vivianne, Trollmo, Christina, Korotkova, Marina, Jakobsson, Per-Johan, Tak, Paul-Peter
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029314/ https://www.ncbi.nlm.nih.gov/pubmed/21298002 http://dx.doi.org/10.1371/journal.pone.0016378

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