Secreted Amyloid Precursor Protein β and Secreted Amyloid Precursor Protein α Induce Axon Outgrowth In Vitro through Egr1 Signaling Pathway

BACKGROUND: sAPPα released after α secretase cleavage of Amyloid Precursor Protein (APP) has several functions including the stimulation of neurite outgrowth although detailed morphometric analysis has not been done. Two domains involved in this function have been described and are present in sAPPβ...

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Detalles Bibliográficos
Autores principales: Chasseigneaux, Stéphanie, Dinc, Levent, Rose, Christiane, Chabret, Claude, Coulpier, Fanny, Topilko, Piotr, Mauger, Gweltas, Allinquant, Bernadette
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029320/
https://www.ncbi.nlm.nih.gov/pubmed/21298006
http://dx.doi.org/10.1371/journal.pone.0016301

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