Cargando…

Bifunctional Avidin with Covalently Modifiable Ligand Binding Site

The extensive use of avidin and streptavidin in life sciences originates from the extraordinary tight biotin-binding affinity of these tetrameric proteins. Numerous studies have been performed to modify the biotin-binding affinity of (strept)avidin to improve the existing applications. Even so, (str...

Descripción completa

Detalles Bibliográficos
Autores principales:	Leppiniemi, Jenni, Määttä, Juha A. E., Hammaren, Henrik, Soikkeli, Mikko, Laitaoja, Mikko, Jänis, Janne, Kulomaa, Markku S., Hytönen, Vesa P.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029397/ https://www.ncbi.nlm.nih.gov/pubmed/21305032 http://dx.doi.org/10.1371/journal.pone.0016576

Ejemplares similares

Zebavidin - An Avidin-Like Protein from Zebrafish
por: Taskinen, Barbara, et al.
Publicado: (2013)

Modification of the loops in the ligand-binding site turns avidin into a steroid-binding protein
por: Riihimäki, Tiina A, et al.
Publicado: (2011)

Structure of Bradavidin – C-Terminal Residues Act as Intrinsic Ligands
por: Leppiniemi, Jenni, et al.
Publicado: (2012)

Avidin related protein 2 shows unique structural and functional features among the avidin protein family
por: Hytönen, Vesa P, et al.
Publicado: (2005)

A Novel Chimeric Avidin with Increased Thermal Stability Using DNA Shuffling
por: Taskinen, Barbara, et al.
Publicado: (2014)

Structural and functional characteristics of xenavidin, the first frog avidin from Xenopus tropicalis
por: Määttä, Juha AE, et al.
Publicado: (2009)

Design of modular gellan gum hydrogel functionalized with avidin and biotinylated adhesive ligands for cell culture applications
por: Gering, Christine, et al.
Publicado: (2019)

Chimeric Avidin – NMR Structure and Dynamics of a 56 kDa Homotetrameric Thermostable Protein
por: Tossavainen, Helena, et al.
Publicado: (2014)

Construction of Chimeric Dual-Chain Avidin by Tandem Fusion of the Related Avidins
por: Riihimäki, Tiina A., et al.
Publicado: (2011)

pH-Dependent Deformations of the Energy Landscape of Avidin-like Proteins Investigated by Single Molecule Force Spectroscopy
por: Köhler, Melanie, et al.
Publicado: (2014)

Chicken genome analysis reveals novel genes encoding biotin-binding proteins related to avidin family
por: Niskanen, Einari A, et al.
Publicado: (2005)

Structural characterization of core-bradavidin in complex with biotin
por: Agrawal, Nitin, et al.
Publicado: (2017)

Biochemical and Biophysical Characterization of Carbonic Anhydrase VI from Human Milk and Saliva
por: Yrjänäinen, Alma, et al.
Publicado: (2022)

Bacterial avidins are a widely distributed protein family in Actinobacteria, Proteobacteria and Bacteroidetes
por: Laitinen, Olli H., et al.
Publicado: (2021)

Characterization of porphobilinogen deaminase mutants reveals that arginine-173 is crucial for polypyrrole elongation mechanism
por: Bustad, Helene J., et al.
Publicado: (2021)

Improving the Immunogenicity of the Mycobacterium bovis BCG Vaccine by Non-Genetic Bacterial Surface Decoration Using the Avidin-Biotin System
por: Liao, Ting-Yu Angela, et al.
Publicado: (2015)

Improved antifouling properties and selective biofunctionalization of stainless steel by employing heterobifunctional silane-polyethylene glycol overlayers and avidin-biotin technology
por: Hynninen, Ville, et al.
Publicado: (2016)

Molecular features of steroid-binding antidins and their use for assaying serum progesterone
por: Agrawal, Nitin, et al.
Publicado: (2019)

Identification and characterization of a novel zebrafish (Danio rerio) pentraxin–carbonic anhydrase
por: Patrikainen, Maarit S., et al.
Publicado: (2017)

Structure and characterization of a novel chicken biotin-binding protein A (BBP-A)
por: Hytönen, Vesa P, et al.
Publicado: (2007)

Structural insights into the substrate-binding proteins Mce1A and Mce4A from Mycobacterium tuberculosis
por: Asthana, Pooja, et al.
Publicado: (2021)

Azidobupramine, an Antidepressant-Derived Bifunctional Neurotransmitter Transporter Ligand Allowing Covalent Labeling and Attachment of Fluorophores
por: Kirmeier, Thomas, et al.
Publicado: (2016)

Characterisation of a common hotspot variant in acute intermittent porphyria sheds light on the mechanism of hydroxymethylbilane synthase function
por: Christie, Marthe S., et al.
Publicado: (2022)

Internalization of novel non-viral vector TAT-streptavidin into human cells
por: Rinne, Johanna, et al.
Publicado: (2007)

Structural and functional insights into the unique CBS–CP12 fusion protein family in cyanobacteria
por: Hackenberg, Claudia, et al.
Publicado: (2018)

Hepcidin is potential regulator for renin activity
por: Piesanen, Jaakko, et al.
Publicado: (2022)

Bifunctional crosslinking ligands for transthyretin
por: Mangione, P. Patrizia, et al.
Publicado: (2015)

Comparison of the Chase Effects of Avidin, Streptavidin, Neutravidin, and Avidin‐Ferritin on a Radiolabeled Biotinylated Anti‐tumor Monoclonal Antibody
por: Kobayashi, Hisataka, et al.
Publicado: (1995)

Host Cell Calpains Can Cleave Structural Proteins from the Enterovirus Polyprotein
por: Laajala, Mira, et al.
Publicado: (2019)

Characterization of the first beta-class carbonic anhydrase from an arthropod (Drosophila melanogaster) and phylogenetic analysis of beta-class carbonic anhydrases in invertebrates
por: Syrjänen, Leo, et al.
Publicado: (2010)

Effects of Biotin-Avidin Interactions on Hydrogel Swelling
por: Alina, Talaial B., et al.
Publicado: (2020)

Biotin-Avidin-Mediated Capture of Microspheres on Polymer Fibers
por: Ahrens, Lucas, et al.
Publicado: (2019)

Functionalized Scout Fragments for Site-Specific Covalent Ligand Discovery and Optimization
por: Crowley, Vincent M., et al.
Publicado: (2021)

Lifestyle factors and site-specific risk of hip fracture in community dwelling older women – a 13-year prospective population-based cohort study
por: Määttä, Mikko, et al.
Publicado: (2012)

How Force Might Activate Talin's Vinculin Binding Sites: SMD Reveals a Structural Mechanism
por: Hytönen, Vesa P, et al.
Publicado: (2008)

Biochemical modifications of avidin improve pharmacokinetics and biodistribution, and reduce immunogenicity.
por: Chinol, M., et al.
Publicado: (1998)

SpyAvidin Hubs Enable Precise and Ultrastable Orthogonal Nanoassembly
por: Fairhead, Michael, et al.
Publicado: (2014)

The Biotin–Avidin Interaction in Biotinylated Gold Nanoparticles and the Modulation of Their Aggregation
por: Lyu, Yanchao, et al.
Publicado: (2021)

Assessment of the Relaxation-Enhancing Properties of a Nitroxide-Based Contrast Agent TEEPO-Glc with In Vivo Magnetic Resonance Imaging
por: Soikkeli, Maiju, et al.
Publicado: (2019)

Combining the Physical Adsorption Approach and the Covalent Attachment Method to Prepare a Bifunctional Bioreactor
por: Dong, Mengxing, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_2f6tl7kpnpgmq343g1frir30r5