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Conformational Conversion during Amyloid Formation at Atomic Resolution
Numerous studies of amyloid assembly have indicated that partially folded protein species are responsible for initiating aggregation. Despite their importance, the structural and dynamic features of amyloidogenic intermediates and the molecular details of how they cause aggregation remain elusive. H...
Autores principales: | Eichner, Timo, Kalverda, Arnout P., Thompson, Gary S., Homans, Steve W., Radford, Sheena E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029554/ https://www.ncbi.nlm.nih.gov/pubmed/21255727 http://dx.doi.org/10.1016/j.molcel.2010.11.028 |
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