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A physical model for PDZ-domain/peptide interactions

The PDZ domain is an interaction motif that recognizes and binds the C-terminal peptides of target proteins. PDZ domains are ubiquitous in nature and help assemble multiprotein complexes that control cellular organization and signaling cascades. We present an optimized energy function to predict the...

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Detalles Bibliográficos
Autores principales: Kaufmann, Kristian, Shen, Nicole, Mizoue, Laura, Meiler, Jens
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029681/
https://www.ncbi.nlm.nih.gov/pubmed/20461427
http://dx.doi.org/10.1007/s00894-010-0725-5