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A physical model for PDZ-domain/peptide interactions
The PDZ domain is an interaction motif that recognizes and binds the C-terminal peptides of target proteins. PDZ domains are ubiquitous in nature and help assemble multiprotein complexes that control cellular organization and signaling cascades. We present an optimized energy function to predict the...
Autores principales: | Kaufmann, Kristian, Shen, Nicole, Mizoue, Laura, Meiler, Jens |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029681/ https://www.ncbi.nlm.nih.gov/pubmed/20461427 http://dx.doi.org/10.1007/s00894-010-0725-5 |
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