Evidence for anti-angiogenic and pro-survival functions of the cerebral cavernous malformation protein 3

Mutations in CCM1, CCM2, or CCM3 lead to cerebral cavernous malformations, one of the most common hereditary vascular diseases of the brain. Endothelial cells within these lesions are the main disease compartments. Here, we show that adenoviral CCM3 expression inhibits endothelial cell migration, pr...

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Detalles Bibliográficos
Autores principales: Schleider, Elisa, Stahl, Sonja, Wüstehube, Joycelyn, Walter, Ulrich, Fischer, Andreas, Felbor, Ute
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029799/
https://www.ncbi.nlm.nih.gov/pubmed/20862502
http://dx.doi.org/10.1007/s10048-010-0261-6

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