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Alpha-synuclein deficiency leads to increased glyoxalase I expression and glycation stress
The presynaptic protein alpha-synuclein has received much attention because its gain-of-function is associated with Parkinson’s disease. However, its physiological function is still poorly understood. We studied brain regions of knock-out mice at different ages with regard to consistent upregulation...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
SP Birkhäuser Verlag Basel
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029823/ https://www.ncbi.nlm.nih.gov/pubmed/20711648 http://dx.doi.org/10.1007/s00018-010-0483-7 |