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Parvovirus B19 Nonstructural Protein-Induced Damage of Cellular DNA and Resultant Apoptosis
Parvovirus B19 is a widespread virus with diverse clinical presentations. The viral nonstructural protein, NS1, binds to and cleaves the viral genome, and induces apoptosis when transfected into nonpermissive cells, such as hepatocytes. We hypothesized that the cytotoxicity of NS1 in such cells resu...
Autores principales: | Poole, Brian D., Kivovich, Violetta, Gilbert, Leona, Naides, Stanley J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3030141/ https://www.ncbi.nlm.nih.gov/pubmed/21278893 |
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